Let’s Talk Turkey… Does Tryptophan Really Make You Tired?

It's the season of indulgence: lots of food, desserts, family, and fun. It's also time to wonder if the Tryptophan is going to causing napping.
Turkey and tryptophan feature

Tryptophan, an essential amino acid, has been the subject of various discussions and misconceptions, especially surrounding its role in sleep and mood regulation. Often associated with Thanksgiving turkey-induced drowsiness, tryptophan has garnered a reputation that goes beyond its actual impact on the human body. In this article, we will delve into the truth about tryptophan, exploring the facts, dispelling myths, and examining both the benefits and potential adverse effects associated with this amino acid.

Tryptophan: The Basics

Tryptophan molecule

Tryptophan is one of the nine essential amino acids that the human body cannot produce on its own and must be obtained from diet. It plays a crucial role in the synthesis of serotonin, a neurotransmitter that contributes to mood regulation, among other functions. While it is true that turkey contains tryptophan, it is essential to understand that many other foods, both animal and plant-based, also provide this amino acid. Foods that are high in tryptophan include:

  • Eggs
  • Cheese
  • Milk
  • Fish, especially salmon, and tuna
  • Poultry, especially chicken, and turkey
  • Red meat and pork
  • Tofu and soy products (soybeans)
  • Grains, including quinoa and oats

Myths and Misconceptions

Turkey-induced Sleepiness

One of the most prevalent myths is the belief that consuming turkey induces a state of drowsiness. While it is true that turkey contains tryptophan, the amount ingested during a typical meal is not sufficient to cause significant sleepiness. Other amino acids present in the meal, as well as the overall caloric intake, play a more substantial role in determining post-meal fatigue.

Tryptophan Supplements as a Cure for Insomnia

Some individuals believe that taking supplements can be a natural remedy for insomnia. While tryptophan is a precursor to serotonin, the scientific evidence supporting its efficacy as a standalone treatment for sleep disorders is inconclusive. Other factors, such as lifestyle, sleep hygiene, and overall health, also significantly influence sleep quality.

Benefits of Tryptophan

Foods high in Tryptophan

Mood Regulation

Tryptophan is a precursor to serotonin, a neurotransmitter associated with mood regulation. Consuming foods rich in tryptophan, such as poultry, eggs, and certain dairy products, can contribute to the production of serotonin and may play a role in supporting emotional well-being.

Cognitive Function

Tryptophan is involved in the synthesis of neurotransmitters, including serotonin and melatonin, which are crucial for cognitive function and sleep-wake cycles. A balanced intake through a well-rounded diet may positively impact cognitive processes.

Immune System Support

Tryptophan is also a precursor to niacin, a B vitamin important for immune system function. Adequate levels in the diet contribute to the body’s ability to produce niacin, supporting immune health.

Possible Adverse Effects

napping after thanksgiving dinner

Serotonin Syndrome

Excessive intake of tryptophan, either through supplements or certain foods, can lead to a condition known as serotonin syndrome. This rare but serious condition results from an excess of serotonin in the body, leading to symptoms such as confusion, rapid heart rate, and in severe cases, life-threatening complications.

Interactions with Medications

Individuals taking certain medications, such as selective serotonin reuptake inhibitors (SSRIs) or monoamine oxidase inhibitors (MAOIs), should be cautious with tryptophan supplementation. Combining these substances can lead to an excessive increase in serotonin levels, potentially causing adverse effects.

Allergic Reactions

While rare, some individuals may be allergic to tryptophan, experiencing symptoms such as itching, swelling, or difficulty breathing. Anyone with a known sensitivity to this amino acid should exercise caution and seek medical advice.

Wrapping Up

cartoon turkey napping

Tryptophan, often surrounded by myths and misconceptions, is a vital amino acid with various benefits when consumed in appropriate amounts. While it is true that it plays a role in mood regulation and sleep, attributing post-Thanksgiving meal drowsiness solely to this amino acid is an oversimplification. As with any nutrient, balance is key, and it is crucial to obtain tryptophan through a diverse and well-rounded diet rather than relying on supplements.

Understanding the truth about tryptophan allows individuals to make informed choices about their dietary habits, considering both the potential benefits and risks associated with this essential amino acid. As with any health-related matter, consulting with a healthcare professional is advisable to ensure personalized advice based on individual health conditions and needs.

Read Next:

Is it Time to Trim the Turkey Neck?

6 Easy Steps to Prepare the Perfect Thanksgiving Turkey

Is It Normal… to Exercise Like Crazy and Still Have a Belly?


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